Archives2022Vol. 62, № 3pp. 287–294

Article

Biological Effects Evaluation of Ozone and Electromagnetic Pulses Combined Exposure from Electric discharge Unit

Gavrish N.N.1, Ushakov I.B.2, Maksimov S.G.1, Perov S. Yu.3, Belaya O.V.3

1Central Scientific Research Institute of the Ministry of Defense, Sergiev Posad, Russia 2A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia 3 Izmerov Research Institute of Occupational Health, Moscow, Russia

Abstract

The pilot research results of the biological effects of pulsed EMF and ozone combined exposure in the acute experiment are presented. The combined exposure conditions were produced by the electric discharge unit operation during 100 minutes. The biological objects were laboratory male rats with body weight of 200–280 g. The clinical condition of laboratory animals, their orientating-exploratory activity, pathomorphological and hematological parameters, the antioxidant system markers were assessed 40 minutes after the end of exposure. The behavior inhibition, pronounced pilomotor reaction, lightening of hematological samples color as well as the increase the of the heart and intestines macropreparations activity automatism period were observed in experimental group rats in comparison with the sham exposure group rats. The antioxidant defense system activation was also observed in the dynamics of biochemical markers. The obtained results indicated need to following research of electric discharge factors combined exposure effects for occupational hygienic and therapeutic purposes.

Keywords

Corona discharge, broadband electromagnetic fields, ozone, combined effect on the body, electric discharge installation

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