Archives2023Vol. 63, № 3pp. 311–317

Article

Foreshadowing the Future of Genetic Engineering and Radiobiology: 100 Years From the Beginning of N.V. Timofeeff-Ressovsky's Scientific Work

I. D. Klabukov1,2,3, A. O. Yakimova1, D. S. Baranovskii1,2, E. M. Yatsenko1, V. A. Petrov1, L. P. Zhavoronkov1, S. A. Ivanov1,2, P. V. Shegai1,4, A. D. Kaprin1,2,4

1A. Tsyb National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, Obninsk, Russia 2Рeoples’ Friendship University of Russia (RUDN University), Moscow, Russia 3Obninsk Institute of Nuclear Power Engineering of the National Research Nuclear University MEPhI, Obninsk, Russia 4P. Hertsen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centrе of the Ministry of Health of the Russian Federation, Moscow, Russia

Abstract

The year 2021 was marked with a significant date – 100 years ago, brilliant radiobiologist and geneticist N.V. Timofeeff-Ressovsky started his scientific work. Among the new directions developed by him from 1921 to 1981 were physical biology, basic principles of genetic engineering, amplifier principle, and population radiobiology. It is noteworthy that many of his ideas were developed in the former Department of Radiation Genetics and General Radiobiology of the Institute of Medical Radiology in Obninsk, which is now called the Experimental Sector of the A. Tsyb Medical Radiological Research Centrе. Our work reveals the interconnections of Timofeeff-Ressovsky’s works with the activities of his contemporaries and productive ideas of today.

Keywords

Genetic engineering, Obninsk, radiobiology, radioresistance, Timofeev-Ressovsky

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