Archives2023Vol. 63, № 3pp. 250–254

Article

Risk of Depressions after Radiation

G. D. Zasukhina1, T. N. Maximova2

1Vavilov Institute of General Genetics, Russian Academy of Science, Moscow, Russia 2Sechenov First Moscow State Medical University, Moscow, Russia

Abstract

The review provides data from a number of authors on the risk of developing psychogenic disorders, mainly depression as the most severe pathology, after accidents at nuclear power plants: Three Mile Island, Chernobyl, Fukushima. At the same time, it is important to develop depression even many years after the accident. The second part of the review provides information on the development of depression in patients with head and neck cancer who received head radiotherapy. The number of pathologies in this group significantly exceeds the indicator of the development of pathologies in patients with other types of cancer. The role of noncoding RNAs in the pathogenesis of radio-induced depression is discussed. They are supposed to be used as targets for specific therapy of depression.

Keywords

Depression, radiation, accidents at nuclear power plants

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