Radiation biology. Radioecology
ISSN: 0869-8031

Archives → 2023 → Vol. 63, № 1 → pp. 80-86

Article

Stimulation of Mesenchymal Stem Cells Proliferation from the Femur of Wistar Rats by Nanosecond Microwave Radiation: Dependence on the Number of Pulses

А. А. Gostyuhina1,2,3, М. А. Bolshakov1,3, А. V. Samoylova1,3,4, O. S. Doroshenko2,3, M. V. Svetlik3,4, О. P. Kutenkov1, K. V. Zaitsev2, and V. V. Rostov1

1Institute of High Current Electronics, Siberian Branch of the Russian Academy of Sciences, Tomsk, Russia 2Federal Scientific and Clinical Center of Medical Rehabilitation and Balneology of the Federal Medical and Biological Agency of Russia, Moscow, Russia 3National Research Tomsk State University, Tomsk, Russia 4Siberian State Medical University of the Ministry of Health of the Russian Federation, Tomsk, Russia

Abstract

The effect of nanosecond repetitively pulsed microwave radiation (RPM, 50–4000 pulses, pulse repetition rate of 13 Hz, peak power flux density of 140 W/cm2, carrier frequency of 10 GHz) on the stimulation of me-senchymal stem cells (MSC) proliferation was studied. The effect of exposure was assessed by the change in the number of cells in the culture after a single irradiation with a different number of pulses. The most pronounced effect exerted by the impact with 100 and 50 pulses, and the effect is realized with a maximum speed after 24 hours.

Keywords

Mesenchymal stem cells, stimulation of proliferation, nanosecond microwave pulses, number of pulses, rats

Current Issue

Vol. 63, № 4

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