Archives → 2022 → Vol. 62, № 6 → pp. 578–590
Article
Effect of Ionizing Radiation on Cytokine Status (Literature Review)
Rybkina V. L., Azizova T. V., Adamova G. V., Oslina D. S.
Southern Urals Biophysics Institute, Ozyorsk, Russia
Abstract
The paper reviews data on the cytokine expression in humans and animals after radiation exposure. Cytokines are biologically active hormone-like proteins regulating a wide range of processes in the body. The main functions of cytokines are regulation of the immune response and inflammatory processes, participation in embryogenesis. Cytokines can affect the cell radiosensitivity, the frequency and type of radiation-induced tissue reactions, and the genome damage. Changes in the expression of cytokines can persist for a long time after radiation exposure and are mainly pro-inflammatory in nature. The study of cytokine helps to understand the
mechanisms of development of the immediate and long-term effects of radiation exposure in order to minimize or prevent them.
Keywords
Cytokines, ionizing radiation, cytokine expression, cytokine profile, immune status
Current Issue
FAQs
Yes, authors are provided with pdf files. The files are sent to the authors' addresses specified in the file "Information about authors".
No.