Archives → 2020 → V. 60. №3. → pp. 265–269
Article
Biodosimetry technique based on CD3+CD4+ Lymphocyte Levels for Assessment of Chronic Radiation Exposure
S. V. Osovets, V. L. Rybkina, and T. V. Azizova
Southern Urals Biophysics Institute affiliated at the Federal Medical and Biological Agency of Russia, Ozyorsk, Russia
Abstract
39 former workers of the Mayak PA who had been occupationally exposed to gamma rays over prolonged periods were involved in the study aimed to develop a technique for biological dosimetry. An exponential relationship «CD3+CD4+ level–absorbed radiation dose» was set as a basic mathematical model for estimation
of external exposure doses from gamma rays. The study demonstrated that doses estimated with the exponential model were consistent with individual doses that had been estimated with a physical dosimetry method for Mayak PA workers earlier. The observed relationship may be used as a calibration curve for estimation of
absorbed doses of chronic external exposure from gamma rays accumulated by nuclear workers.
Keywords
biological dosimetry, Т-helpers (СD3+CD4+), external γ-ray exposure, exponential relationship, calibration curve
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