Archives → 2020 → V. 60. № 1. → pp. 51-62
Article
The Role of the Typological Characteristics of Rats Higher Nervous Activity in the Neurobiologic Effects of Combined Impact of Antiorthostatic Suspension, γ-Rays, Protons and Carbon 12C Ions
A. S. Shtemberg1, A. A. Perevezentsev1, K. B. Lebedeva-Georgievskaya1, O. V. Mitrofanova1, V. S. Kudrin1 and A. S. Bazyan1,2
1Institute of Biomedical Problems, Russian Academie of Sciences, Moscow, Russia 2Institute of Higher Nervous Activity and Neurophysiology, Russian Academie of Sciences, Moscow, Russia
Abstract
The investigation of role of the influence of typological characteristics of rats higher nervous activity on neurobiological effects (rats behavior and its neurochemical mechanisms) of the combined impact of 10-days antiorthostatic suspension, gamma, high energy protons and carbon 12C ions irradiation were demonstrated that 12C ions irradiation produced the deep disturbances of the rats behavior in rats belong to excitable, anxiety, emotional type. In experiment with protons irradiation the differences between typological groups were less visible, however the passive-defense behavior in rats of experimental groups were also increased. These changes were accompanied by decreasing of monoamine metabolism in prefrontal cortex.
Keywords
antiorthostatic suspension, gamma-irradiation, high energy protons, carbon ions 12C, rats typological characteristics of higher nervous activity, rats behavior, monoamine metabolism
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