Archives → 2020 → V. 60. № 1. → pp. 42-50
Article
Analysis of Incidence Risk for Different Types of Stroke Among “Мayak” Worker Cohort
M. B. Moseeva, E. S. Grigoryeva and T. V. Azizova
Southern Urals Biophysics Institute Russian Federal Medical Biological Agency, Ozyorsk, Russia
Abstract
The present paper presents incidence risk estimates for different stroke type among cohort of 22377 Mayak workers occupationally exposed to prolonged radiation and followed up until the end of 2013. Information about work histories and estimates of liver absorbed dose from external and internal radiations were obtained from the «Dosimtery System for Mayak Workers 2013»; medical and life style factors were obtained from «Clinic» medical dosimetry database. During the follow-up period 221 cases of intracerebral hemorrhage (ICH), 1463 cases of brain cerebral infarction (BI) and 342 cases of non-specified stroke (NS) were registered in the study cohort. It was shown that ICH, BI and NS incidence risks in the study cohort depended statistically significantly on such non-radiation factors as gender, age, calendar period, duration of work at main facilities, smoking, alcohol assumption, body mass index, and co-morbidity (arterial hypertension and diabetes), which agreed with the literature data. Analyses did not reveal an effect of external gamma ray exposure on ICH and BI incidence. However, there was a NS relative risk (RR) statistically significantly below one in groups of workers exposed to external gamma rays in total absorbed liver doses above 0.20 Gy as compared with the workers exposed in doses below 0.10 Gy, which was difficult to explain or confirm/reject by other studies. RR for BI incidence was statistically significantly above one in groups of workers exposed to internal alpha particle radiation in total absorbed liver dose above 0.10 Gy as compared with workers exposed at lower doses. There was no effect of internal exposure on ICH and NS incidence. Findings agreed with the results obtained earlier in the cohort of Mayak workers.
Keywords
stroke, risk, gamma rays, alpha particles, Mayak PA, occupational prolonged radiation exposure
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