Archives → 2018 → Vol. 58, No. 2 → pp. 117-125
Article
Cytogenetic indicators in patients and healthy residents of the bryan and kaluga regions contaminated by radionuclides
Ivanova T.I.1, Mkrtchyan L.S.1, Antoschina M.M.1, Fesenko E.V.1, Horohorina V.A.1, Ovsyannikova N.S.1, Parshin V.S.1, Sychenkova H.I.1, Ragulin Yu.A.1, Zharikova I.A.1, Ryabchenko N.I.1, Krikunova L.I.1
1A.F. Tsyb Medical Radiological Research Center, Ministry of Health of the Russian Federation, Obninsk, Russia
Abstract
From 2014 to 2015 cytogenetic analysis of 155 women (average age 43 years) living in the Bryansk (Klintsy) and Kaluga regions (Lyudinovo) radiocontaminated after the Chernobyl accident had been conducted. There were mainly women with benign diseases of the thyroid gland and organs of the female reproductive system, including the mammary gland. The aim of the study is the assessment of the peripheral blood chromosomal aberration frequency (per 100 cells) depending on the radioactive contamination area. It has been found that the level of aberrations does not differ from the control values (54 women of a similar age living in Moscow and Obninsk) in the women living in both contaminated regions. The dicentric frequency in a more contaminated area (Klintsy) was significantly increased as compared with the control (р = 0.01). There were no differences in the dicentric frequency between the areas (p = 0.57). Further health examination of the residents of contaminated areas is advisable with combination of cytogenetic studies.
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